Tula virus phylogeography

Extensive host sharing of central European Tula virus.

To examine the host association of Tula virus (TULV), a hantavirus present in large parts of Europe, we investigated a total of 791 rodents representing 469 Microtus arvalis and 322 Microtus agrestis animals from northeast, northwest, and southeast Germany, including geographical regions with sympatric occurrence of both vole species, for the presence of TULV infections. Based on serological in...

Tula Hantavirus Nucleocapsid Protein

Phylogeography of Crimean Congo Hemorrhagic Fever Virus

Crimean Congo hemorrhagic fever virus (CCHFV) is one of the most severe viral zoonozes. It is prevalent throughout Africa, Asia and southern Europe. Limited availability of sequence data has hindered phylogeographic studies. The complete genomic sequence of all three segments of 14 Crimean Congo hemorrhagic fever virus strains isolated from 1958-2000 in Russia, Central Asia and Africa was ident...

Isolation and characterization of Tula virus, a distinct serotype in the genus

A Vero E6 cell culture isolate of Tula virus (TUL), a hantavirus first detected in European common voles (hficrotus arvalis and hr. rossiaemeridionolis) by RT-PCR was obtained after initial passaging of TULinfected vole lung samples in laboratory-colonized hl. arvalis. TUL was defined as a classical serotype by a cross-focus-reduction neutralization test (FRNT) and was also shown to be distinct...

Tula virus in populations of small terrestrial mammals in a rural landscape.

Over 5 years (2000-2004), populations of small mammals from a rural landscape in southern Moravia (Czech Republic) were investigated for the presence of Tula virus (TULV) antigen using the ELISA set Hantagnost. In total, 1566 individuals from 10 species were examined. The prevalence in the common vole (Microtus arvalis Pallas 1778), the main reservoir of TULV, was 10% (n = 871). The prevalence ...